A xx Male (SRY+) Disorder of Sexual Development; A Case Report and Review of Articles

Mohseni Rad, Hamed; Hosseiniasl, said

doi:10.30699/acadpub.jru.4.2.101

Volume 4, Issue 2 (Fall & Winter 2020) J Res Urol 2020, 4(2): 101-107 | Back to browse issues page

‎ 10.30699/acadpub.jru.4.2.101

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Mohseni Rad H, Hosseiniasl S. A xx Male (SRY+) Disorder of Sexual Development; A Case Report and Review of Articles. J Res Urol 2020; 4 (2) :101-107
URL: http://urology.umsha.ac.ir/article-1-83-en.html

A xx Male (SRY+) Disorder of Sexual Development; A Case Report and Review of Articles

Hamed Mohseni Rad ^*

¹, Said Hosseiniasl²

1- Assistant Professor, Department of Surgery, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran , sirhamed@hotmail.com
2- Associated Professor, Department of Anatomical Sciences and Pathology, School of Medicine, Ardabil University of Medical science, Ardabil, Iran

Abstract: (3927 Views)

46 XX male DSD which was previously named “de la Chapelle” syndrome is a rare disorder found in every 20000 infant males. Sixty to ninety percent of 46-XX males are fully virilized and have normal genitalia except small testicles. This report explains a 40 year-old infertile man presented with small testes and azoospermia but no signs of undervirilization. His had hypergonadotropic hypogonadism. Lymphocytes were cultured in GibcoTM RPMI Medium 1640 for 7 days for karyotyping which revealed 46XX. In conclusion, not to miss genetic defects like 46, XX male DSD, karyotype test should be considered in cases with atrophic testicles plus azoospermia even in adult men.

Keywords: 46xx male DSD, Azoospermia, SRY, Infertility, Testis atrophy

Full-Text [PDF 1065 kb] (1861 Downloads)

Type of Study: case report | Subject: Andrology
Received: 2021/07/28 | Accepted: 2021/08/1 | Published: 2021/09/4

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