Volume 5, Issue 1 (Spring & Summer 2021)
J Res Urol 2021, 5(1): 29-34 |
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Pour Amiri R, Raeisi R, Karimi L, Naderi M, Sanaei Z, Sheida F. Metabolic Risk Factors in Infants and Children with Kidney Stones. J Res Urol 2021; 5 (1) :29-34
URL: http://urology.umsha.ac.ir/article-1-93-en.html
URL: http://urology.umsha.ac.ir/article-1-93-en.html
Rahim Pour Amiri1 
, Roya Raeisi * 2, Lotfollah Karimi3 , Mostafa Naderi1 , Zahra Sanaei4 , Fatemeh Sheida1
, Roya Raeisi * 2, Lotfollah Karimi3 , Mostafa Naderi1 , Zahra Sanaei4 , Fatemeh Sheida1
1- Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2- Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran , r_reisi2@yahoo.com
3- Department of Basic Sciences, Hamedan University of Technology, Hamedan, Iran
4- Department of Basic Sciences, Hamadan University of Technology, Hamadan, Iran and Department of Social Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2- Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran , r_reisi2@yahoo.com
3- Department of Basic Sciences, Hamedan University of Technology, Hamedan, Iran
4- Department of Basic Sciences, Hamadan University of Technology, Hamadan, Iran and Department of Social Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract: (1931 Views)
Background and Objective: In spite of adult renal stones, in pediatric renal stones, most cases have a hereditary background. The evaluation of metabolic risk factors in children with renal stone disease is the basis of medical treatment aimed at preventing recurrent stone events and the growth of preexisting calculi. Therefore, this study was conducted to investigate metabolic risk factors among infants and children with kidney stones in Hamadan Province, Iran, so that it can be the basis for further studies to suggest the elimination of unnecessary diagnostic tests.
Materials and Methods: A total of 270 children diagnosed with urinary stones were entered into the study. After recording demographic information, laboratory tests of patients' serum for calcium, phosphorus, sodium, potassium, bicarbonate, uric acid, magnesium, creatinine, and alkaline phosphatase were performed. Moreover, patients' urine was measured for the excretion of random morning samples, such as calcium, oxalate, magnesium, sodium, and uric acid.
Results: It was revealed that the male gender had a significant relationship with hypercalciuria and hyperoxaluria. Furthermore, there was a significant relationship of stone size with impaired urine analysis and positive urine culture.
Conclusion: Based on the results of this study, urinary metabolic risk factors were widely present in children with urinary stones, and hypercalciuria was the most commonly found disorder. It is recommended that in the evaluation of kidney stones in children, after ruling out the urinary tract abnormalities and infections, metabolic examination of urine be performed, including random measurement of calcium to creatinine in the morning urine, in order to reduce the economic consequences of extensive testing.
Materials and Methods: A total of 270 children diagnosed with urinary stones were entered into the study. After recording demographic information, laboratory tests of patients' serum for calcium, phosphorus, sodium, potassium, bicarbonate, uric acid, magnesium, creatinine, and alkaline phosphatase were performed. Moreover, patients' urine was measured for the excretion of random morning samples, such as calcium, oxalate, magnesium, sodium, and uric acid.
Results: It was revealed that the male gender had a significant relationship with hypercalciuria and hyperoxaluria. Furthermore, there was a significant relationship of stone size with impaired urine analysis and positive urine culture.
Conclusion: Based on the results of this study, urinary metabolic risk factors were widely present in children with urinary stones, and hypercalciuria was the most commonly found disorder. It is recommended that in the evaluation of kidney stones in children, after ruling out the urinary tract abnormalities and infections, metabolic examination of urine be performed, including random measurement of calcium to creatinine in the morning urine, in order to reduce the economic consequences of extensive testing.
Type of Study: Research |
Subject:
Pediatric Urology
Received: 2021/12/2 | Accepted: 2022/03/10 | Published: 2021/09/1
Received: 2021/12/2 | Accepted: 2022/03/10 | Published: 2021/09/1
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