Volume 7, Issue 2 (Fall & Winter 2024)
J Res Urol 2024, 7(2): 69-74 |
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Banouei F. Investigating the Effect of Testosterone Supplements used by Bodybuilding Athletes on Urinary Tract Stone Formation: A Two-year Cross-sectional Study. J Res Urol 2024; 7 (2) :69-74
URL: http://urology.umsha.ac.ir/article-1-140-en.html
URL: http://urology.umsha.ac.ir/article-1-140-en.html
Urology & Nephrology Research Center, Hamedan University of Medical Sciences, Hamedan, Iran , farshadbanouei90@gmail.com
Abstract: (410 Views)
Background and Objective: Nowadays, the utilization of exogenous testosterone has progressively gained popularity in diverse sports domains, thereby giving rise to apprehensions regarding its associated risks and potential advantages.
Materials and Methods: In this study, conducted to investigate the impact of testosterone supplementation on urinary tract stone formation and urine compounds, a total of 1,080 athletes were examined in a two-year cross-sectional study. Among them, 495 athletes received testosterone supplementation, while 585 athletes were investigated as non-consumers. Blood and urine samples were collected, and a computed tomography scan was performed to assess the presence of stones.
Results: The findings of this study revealed a noteworthy rise in crystalluria among testosterone users in comparison to non-users (38.2% vs. 2.7%). Moreover, imaging results exhibited a greater occurrence of abnormal findings in testosterone users (25.2% vs. 4.3%), as evidenced by calcification in kidney tissue, pelvic and caliceal stones, ureteral stones, and bladder stones.
Conclusion: While further metabolomic studies are required to establish a conclusive cause-and-effect relationship between testosterone intake and stone formation, this study emphasizes the potential hazards linked to the utilization of exogenous testosterone and underscores the necessity for evidence-based guidelines in the realm of exercise and athletic performance.
Materials and Methods: In this study, conducted to investigate the impact of testosterone supplementation on urinary tract stone formation and urine compounds, a total of 1,080 athletes were examined in a two-year cross-sectional study. Among them, 495 athletes received testosterone supplementation, while 585 athletes were investigated as non-consumers. Blood and urine samples were collected, and a computed tomography scan was performed to assess the presence of stones.
Results: The findings of this study revealed a noteworthy rise in crystalluria among testosterone users in comparison to non-users (38.2% vs. 2.7%). Moreover, imaging results exhibited a greater occurrence of abnormal findings in testosterone users (25.2% vs. 4.3%), as evidenced by calcification in kidney tissue, pelvic and caliceal stones, ureteral stones, and bladder stones.
Conclusion: While further metabolomic studies are required to establish a conclusive cause-and-effect relationship between testosterone intake and stone formation, this study emphasizes the potential hazards linked to the utilization of exogenous testosterone and underscores the necessity for evidence-based guidelines in the realm of exercise and athletic performance.
Type of Study: Research |
Subject:
Andrology
Received: 2023/11/11 | Accepted: 2024/07/31 | Published: 2024/12/16
Received: 2023/11/11 | Accepted: 2024/07/31 | Published: 2024/12/16
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